The three major design differences are: Morphic is more flexible and you can have multiple views whereas in MVC you can only have multiple views of the same model.
In MVC the Views are the objects that user interacts with but in Morphic, every display object is a Morph.
Morphic objects can be easily manipulated and can be composed to create new morphs .
claudia Iriele
Morphic is more flexible. But you can have multiple views in both, and Morphic morphs can be views. Mark Guzdial